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Cellosaurus HEK293T(DMT1) (CVCL_HA71)

[Text version]
Cell line name HEK293T(DMT1)
Synonyms DMT1 Expressing HEK293T Cell Line
Accession CVCL_HA71
Resource Identification Initiative To cite this cell line use: HEK293T(DMT1) (RRID:CVCL_HA71)
Comments Characteristics: Useful to screen for potential iron transport inhibitors (Kerafast=EF4002).
Genetic integration: Method=Transfection; Gene=MGI; MGI:1345279; Slc11a2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=16984886; DOI=10.1016/j.chembiol.2006.08.005; PMCID=PMC2542486
Wetli H.A., Buckett P.D., Wessling-Resnick M.
Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake.
Chem. Biol. 13:965-972(2006)

Cross-references
Cell line collections (Providers) ABM; T6000
Kerafast; EF4002
Encyclopedic resources Wikidata; Q54882492
Entry history
Entry creation01-Dec-2016
Last entry update19-Dec-2024
Version number13