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Cellosaurus MCF-7/E2F1 (CVCL_HA20)

[Text version]
Cell line name MCF-7/E2F1
Accession CVCL_HA20
Resource Identification Initiative To cite this cell line use: MCF-7/E2F1 (RRID:CVCL_HA20)
Comments Population: Caucasian.
Characteristics: Transfected with E2F1 fused at the N-terminus to an HA tag and the estrogen receptor ligand binding domain.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3113; E2F1.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_HA20
Biological sample resources ENCODE; ENCBS106ENC
ENCODE; ENCBS107ENC
Encyclopedic resources Wikidata; Q54904361
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number16