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Cellosaurus MCF-7 eGFP-KLF4 (CVCL_HA17)

[Text version]
Cell line name MCF-7 eGFP-KLF4
Accession CVCL_HA17
Resource Identification Initiative To cite this cell line use: MCF-7 eGFP-KLF4 (RRID:CVCL_HA17)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6348; KLF4.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_HA17
Biological sample resources ENCODE; ENCBS033ECJ
ENCODE; ENCBS949BEW
ENCODE; ENCBS984RGW
Encyclopedic resources Wikidata; Q54904314
Entry history
Entry creation26-Sep-2016
Last entry update10-Sep-2024
Version number13