ID   SIHN-006
AC   CVCL_H947
SY   SI-HN-006; HN006
DR   ChEMBL-Cells; CHEMBL3308668
DR   ChEMBL-Targets; CHEMBL614827
DR   PubChem_Cell_line; CVCL_H947
DR   Wikidata; Q54953476
RX   PubMed=10760816;
RX   PubMed=11497283;
RX   PubMed=15197768;
CC   Doubling time: 35.1 +- 1.7 hours (PubMed=11497283).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   27Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 29-06-23; Version: 12
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RX   PubMed=10760816; DOI=10.1002/(SICI)1097-0215(20000501)86:3<307::AID-IJC2>3.0.CO;2-I;
RA   O-Charoenrat P., Rhys-Evans P.H., Modjtahedi H., Court W., Box G.,
RA   Eccles S.A.;
RT   "Overexpression of epidermal growth factor receptor in human head and
RT   neck squamous carcinoma cell lines correlates with matrix
RT   metalloproteinase-9 expression and in vitro invasion.";
RL   Int. J. Cancer 86:307-317(2000).
//
RX   PubMed=11497283;
RA   O-Charoenrat P., Rhys-Evans P.H., Eccles S.A.;
RT   "Characterization of ten newly-derived human head and neck squamous
RT   carcinoma cell lines with special reference to c-erbB proto-oncogene
RT   expression.";
RL   Anticancer Res. 21:1953-1963(2001).
//
RX   PubMed=15197768; DOI=10.1002/ijc.20228;
RA   O-Charoenrat P., Wongkajornsilp A., Rhys-Evans P.H., Eccles S.A.;
RT   "Signaling pathways required for matrix metalloproteinase-9 induction
RT   by betacellulin in head-and-neck squamous carcinoma cells.";
RL   Int. J. Cancer 111:174-183(2004).
//