ID   Meso-10
AC   CVCL_H668
SY   Meso 10; Meso10; MESO10
DR   BioSamples; SAMEA100887
DR   cancercelllines; CVCL_H668
DR   Cosmic; 1522770
DR   Cosmic; 1541216
DR   GEO; GSM726275
DR   Progenetix; CVCL_H668
DR   Wikidata; Q54905283
RX   PubMed=16475242;
RX   PubMed=21642991;
RX   PubMed=21774103;
CC   Sequence variation: Gene deletion; HGNC; HGNC:950; BAP1; Zygosity=Heterozygous (PubMed=21642991).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
CC   Omics: SNP array analysis.
DI   NCIt; C7376; Pleural malignant mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 19-12-24; Version: 14
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RX   PubMed=16475242; DOI=10.1002/jgm.877; PMCID=PMC1804293;
RA   Adusumilli P.S., Stiles B.M., Chan M.-K., Mullerad M., Eisenberg D.P.,
RA   Ben-Porat L., Huq R., Rusch V.W., Fong Y.-M.;
RT   "Imaging and therapy of malignant pleural mesothelioma using
RT   replication-competent herpes simplex viruses.";
RL   J. Gene Med. 8:603-615(2006).
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RX   PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098;
RA   Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L.,
RA   Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R.,
RA   Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.;
RT   "The nuclear deubiquitinase BAP1 is commonly inactivated by somatic
RT   mutations and 3p21.1 losses in malignant pleural mesothelioma.";
RL   Nat. Genet. 43:668-672(2011).
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RX   PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d;
RA   Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B.,
RA   Rusch V.W., Ladanyi M.;
RT   "Coactivation of receptor tyrosine kinases in malignant mesothelioma
RT   as a rationale for combination targeted therapy.";
RL   J. Thorac. Oncol. 6:864-874(2011).
//