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Cellosaurus St-4 (CVCL_H265)

[Text version]
Cell line name St-4
Accession CVCL_H265
Resource Identification Initiative To cite this cell line use: St-4 (RRID:CVCL_H265)
Comments Part of: JFCR39 cancer cell line panel.
Part of: JFCR45 cancer cell line panel.
Population: Japanese.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr205del (c.613_615delTAT); Zygosity=Unspecified (PubMed=15900046).
Disease Gastric carcinoma (NCIt: C4911)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_Y176 (St-4/cDDP)CVCL_H266 (St-4/CPT)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line

Sugimoto Y., Tsukahara S., Oh-hara T., Isoe T., Tsuruo T.
Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody.
Cancer Res. 50:6925-6930(1990)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

PubMed=15900046; DOI=10.1093/jnci/dji133
Mashima T., Oh-hara T., Sato S., Mochizuki M., Sugimoto Y., Yamazaki K., Hamada J., Tada M., Moriuchi T., Ishikawa Y., Kato Y., Tomoda H., Yamori T., Tsuruo T.
p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.
J. Natl. Cancer Inst. 97:765-777(2005)

PubMed=22336246; DOI=10.1016/j.bmc.2012.01.017
Kong D., Yamori T.
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
Bioorg. Med. Chem. 20:1947-1951(2012)

Chemistry resources ChEMBL-Cells; CHEMBL3307553
ChEMBL-Targets; CHEMBL614166
PubChem_Cell_line; CVCL_H265
Encyclopedic resources Wikidata; Q54955732
Polymorphism and mutation databases Cosmic; 1436022
IARC_TP53; 21647
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number16