ID   MM-RU
AC   CVCL_H242
AS   CVCL_W801
SY   MMRU; RU
DR   EFO; EFO_0022547
DR   cancercelllines; CVCL_H242
DR   Cosmic; 706104
DR   Cosmic; 888844
DR   Cosmic; 2630486
DR   Wikidata; Q54906023
RX   PubMed=1867326;
RX   PubMed=7680081;
RX   PubMed=8219757;
RX   PubMed=8277038;
RX   PubMed=8429233;
RX   PubMed=9141475;
RX   PubMed=10766161;
RX   PubMed=11606052;
RX   PubMed=18497997;
RX   PubMed=15009714;
WW   https://www.abmgood.com/MMRU-Cell-Transfection-Efficiency-details.html
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=15009714).
CC   Omics: Array-based CGH.
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 19-12-24; Version: 18
//
RX   PubMed=1867326; PMCID=PMC1886079;
RA   Byers H.R., Etoh T., Doherty J.R., Sober A.J., Mihm M.C. Jr.;
RT   "Cell migration and actin organization in cultured human primary,
RT   recurrent cutaneous and metastatic melanoma. Time-lapse and image
RT   analysis.";
RL   Am. J. Pathol. 139:423-435(1991).
//
RX   PubMed=7680081;
RA   Vink J., Thomas L., Etoh T., Bruijn J.A., Mihm M.C. Jr.,
RA   Gattoni-Celli S., Byers H.R.;
RT   "Role of beta-1 integrins in organ specific adhesion of melanoma cells
RT   in vitro.";
RL   Lab. Invest. 68:192-203(1993).
//
RX   PubMed=8219757;
RA   Byers H.R., Etoh T., Lee K.W., Mihm M.C. Jr., Gattoni-Celli S.;
RT   "Organ-specific metastases in immunodeficient mice injected with human
RT   melanoma cells: a quantitative pathological analysis.";
RL   Melanoma Res. 3:247-253(1993).
//
RX   PubMed=8277038; DOI=10.1111/j.1346-8138.1993.tb01349.x;
RA   Stender I.-M., Etoh T., Tsuchida T., Nakagawa H., Byers H.R.,
RA   Imokawa G., Ishibashi Y.;
RT   "Metastatic behavior and tumorigenicity of a human melanoma cell line
RT   (MM-RU) after injection into nude mice.";
RL   J. Dermatol. 20:611-617(1993).
//
RX   PubMed=8429233; DOI=10.1111/1523-1747.ep12462776;
RA   Thomas L., Etoh T., Stamenkovic I., Mihm M.C. Jr., Byers H.R.;
RT   "Migration of human melanoma cells on hyaluronate is related to CD44
RT   expression.";
RL   J. Invest. Dermatol. 100:115-120(1993).
//
RX   PubMed=9141475; DOI=10.1016/S0014-5793(97)00290-1;
RA   Katagata Y., Kondo S.;
RT   "Keratin expression and its significance in five cultured melanoma
RT   cell lines derived from primary, recurrent and metastasized
RT   melanomas.";
RL   FEBS Lett. 407:25-31(1997).
//
RX   PubMed=10766161;
RA   Tsao H., Zhang X., Fowlkes K., Haluska F.G.;
RT   "Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous
RT   melanoma cell lines.";
RL   Cancer Res. 60:1800-1804(2000).
//
RX   PubMed=11606052; DOI=10.1006/bbrc.2001.5789;
RA   Hoashi T., Kadono T., Kikuchi K., Etoh T., Tamaki K.;
RT   "Differential growth regulation in human melanoma cell lines by TIMP-1
RT   and TIMP-2.";
RL   Biochem. Biophys. Res. Commun. 288:371-379(2001).
//
RX   PubMed=18497997; DOI=10.3892/ijo_32_6_1343;
RA   Gao K., Lockwood W.W., Li J., Lam W., Li G.;
RT   "Genomic analyses identify gene candidates for acquired irinotecan
RT   resistance in melanoma cells.";
RL   Int. J. Oncol. 32:1343-1349(2008).
//
RX   PubMed=15009714; DOI=10.1046/j.0022-202X.2004.22243.x; PMCID=PMC2586668;
RA   Tsao H., Goel V., Wu H., Yang G., Haluska F.G.;
RT   "Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1
RT   inactivation in melanoma.";
RL   J. Invest. Dermatol. 122:337-341(2004).
//