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Cellosaurus HepG2-GS (CVCL_H214)

[Text version]
Cell line name HepG2-GS
Synonyms GS-HepG2
Accession CVCL_H214
Resource Identification Initiative To cite this cell line use: HepG2-GS (RRID:CVCL_H214)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 4341; GLUL.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): RCB=RCB1681

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S82010
D13S3179,13
D16S53912
TH019
TPOX8,9
vWA17

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Publications

DOI=10.1016/j.enzmictec.2004.08.027
Omasa T., Yamanaka M., Tanimura N., Katakura Y., Kishimoto M., Suga K.-i., Enosawa S.
Expression and amplification of glutamine synthetase gene endows HepG2 cells with ammonia-metabolizing activity for bioartificial liver support system.
Enzyme Microb. Technol. 35:519-524(2004)

Cross-references
Cell line collections (Providers) RCB; RCB1681
Cell line databases/resources CLO; CLO_0050857
cancercelllines; CVCL_H214
Biological sample resources BioSample; SAMN03472118
Encyclopedic resources Wikidata; Q54882850
Entry history
Entry creation11-Feb-2013
Last entry update10-Sep-2024
Version number22