Cellosaurus cell line YOS-M (CVCL

Cellosaurus YOS-M (CVCL_H194)

Cross-references
Cell line name	YOS-M
Accession	CVCL_H194
Resource Identification Initiative	To cite this cell line use: YOS-M (RRID:CVCL_H194)
Comments	Population: Japanese. Doubling time: 5-6 days (PubMed=1486031). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (PubMed=1486031; PubMed=10071072; PubMed=10576511).
Disease	Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_H193 ! YOS-B
Sex of cell	Male
Age at sampling	77Y
Category	Cancer cell line
Publications	PubMed=1486031; DOI=10.1111/j.1365-2141.1992.tb06461.x Yasukawa M., Yanagisawa K., Kohno H., Yakushijin Y., Kondo T., Fujita S. Simultaneous establishment of myeloid and B-lymphoid cell lines with identical chromosome abnormalities from Philadelphia chromosome-positive chronic myelogenous leukaemia. Br. J. Haematol. 82:515-521(1992) PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4 Drexler H.G., MacLeod R.A.F., Uphoff C.C. Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia. Leuk. Res. 23:207-215(1999) PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9 Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G. ABL-BCR expression in BCR-ABL-positive human leukemia cell lines. Leuk. Res. 23:1055-1060(1999) DOI=10.1016/B978-0-12-221970-2.50457-5 Drexler H.G. The leukemia-lymphoma cell line factsbook. (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)
Encyclopedic resources	Wikidata; Q54995467
Polymorphism and mutation databases	Cosmic; 787509
Entry history
Entry creation	11-Feb-2013
Last entry update	19-Dec-2024
Version number	14