Cellosaurus cell line FO1-12 (CVCL

Cellosaurus FO1-12 (CVCL_GZ38)

Cross-references
Cell line name	FO1-12
Synonyms	Fo1-12; FO-1 #12
Accession	CVCL_GZ38
Resource Identification Initiative	To cite this cell line use: FO1-12 (RRID:CVCL_GZ38)
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12177. Population: Caucasian. Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCIt; C44386; Gamma radiation. Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
Sequence variations	Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease	Amelanotic melanoma (NCIt: C3802)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_5619 (MEL-CLS-1)
Sex of cell	Female
Age at sampling	54Y
Category	Cancer cell line
Publications	Patent=US6063375 Gattoni-Celli S., Newton D.A. 3rd, McClay E.F. Semiallogeneic cell hybrids and related methods for treating cancer. Patent number US6063375, 16-May-2000 PubMed=10746551; DOI=10.1097/00002371-200003000-00009 Newton D.A. 3rd, Romano C., Gattoni-Celli S. Semiallogeneic cell hybrids as therapeutic vaccines for cancer. J. Immunother. 23:246-254(2000) PubMed=10983636; DOI=10.1097/00002030-200007280-00005 Grene E., Newton D.A. 3rd, Brown E.A., Berzofsky J.A., Gattoni-Celli S., Shearer G.M. Semi-allogeneic cell hybrids stimulate HIV-1 envelope-specific cytotoxic T lymphocytes. AIDS 14:1497-1506(2000)
Cell line databases/resources	cancercelllines; CVCL_GZ38 TOKU-E; 3586
Encyclopedic resources	Wikidata; Q54835102
Entry history
Entry creation	26-Sep-2016
Last entry update	10-Sep-2024
Version number	13