Cellosaurus cell line LAZ-177 (CVCL

Cross-references
Cell line name	LAZ-177
Synonyms	LAZ 177; LAZ177; HPFH-2
Accession	CVCL_GY94
Resource Identification Initiative	To cite this cell line use: LAZ-177 (RRID:CVCL_GY94)
Comments	From: Lazarus, Herbert; Dana-Farber Cancer Institute; Boston; USA. Population: African American. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene deletion; HGNC; HGNC:4827; HBB; Zygosity=Homozygous (PubMed=6196781). Gene deletion; HGNC; HGNC:4829; HBD; Zygosity=Homozygous (PubMed=6196781).
Disease	Hereditary persistence of fetal hemoglobin (NCIt: C129072) Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome (ORDO: Orphanet_46532)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Transformed cell line
Publications	PubMed=6196781; DOI=10.1073/pnas.80.22.6937; PMCID=PMC390101 Tuan Lo D., Feingold E., Newman M., Weissman S.M., Forget B.G. Different 3' end points of deletions causing delta beta-thalassemia and hereditary persistence of fetal hemoglobin: implications for the control of gamma-globin gene expression in man. Proc. Natl. Acad. Sci. U.S.A. 80:6937-6941(1983)
Encyclopedic resources	Wikidata; Q54901985
Entry history
Entry creation	26-Sep-2016
Last entry update	19-Dec-2024
Version number	11