| Cell line name |
UCDK9B1 |
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| Accession |
CVCL_GY10 |
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| Resource Identification Initiative |
To cite this cell line use: UCDK9B1 (RRID:CVCL_GY10) |
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| Comments |
Problematic cell line: Contaminated. Shown to be a Jurkat derivative (DOI=10.1016/j.leukres.2012.09.007, ICLAC). Originally thought to be of dog origin and to originate from a female Bullmastiff with a lymphoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00540.
Population: Caucasian.
Miscellaneous: Samples were supplied to ICLAC for STR profiling by Kent M. (UCSD) and tested by Hall E. (Genetica DNA Laboratories).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
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| Sequence variations |
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
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| Disease |
Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0065 (Jurkat) |
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| Sex of cell |
Male |
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| Age at sampling |
14Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): ICLAC
Markers:| Amelogenin | X,Y |
| CSF1PO | 11,12,13 |
| D3S1358 | 15,17 |
| D5S818 | 9 |
| D7S820 | 8,12 |
| D8S1179 | 13,14,15 |
| D13S317 | 8,12 |
| D16S539 | 11 |
| D18S51 | 13,20,21,22 |
| D21S11 | 31.2,32.2,33.2,34.2 |
| FGA | 20,21 |
| Penta D | 11,13 |
| Penta E | 10,12 |
| TH01 | 6,9.3 |
| TPOX | 8,10 |
| vWA | 18,19 |
Run an STR similarity search on this cell line |
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| Web pages |
https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
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| Publications | PubMed=22136758; DOI=10.1016/j.leukres.2011.11.004; PMCID=PMC5404115
Zwingenberger A.L., Vernau W., Shi C.-Y., Yan W.-S., Chen X.-B., Gordon I.K., Kent M.S.
Development and characterization of 5 canine B-cell lymphoma cell lines.
Leuk. Res. 36:601-606(2012) DOI=10.1016/j.leukres.2012.09.007
Zwingenberger A.L., Vernau W., Shi C.-Y., Yan W.-S., Chen X.-B., Gordon I.K., Kent M.S.
Corrigendum to 'Development and characterization of 5 canine B-cell lymphoma cell lines' [Leuk. Res. 36(5) (2011) 601-606].
Leuk. Res. 37:120-120(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_GY10
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| Encyclopedic resources |
Wikidata; Q54989602
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| Entry history |
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| Entry creation | 26-Sep-2016 |
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| Last entry update | 02-May-2024 |
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| Version number | 19 |
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