ID   PAZ6
AC   CVCL_GS29
SY   Paz6; PAZ-6
DR   ABM; T0729
DR   GEO; GSM1543670
DR   GEO; GSM1543671
DR   Wikidata; Q54938334
RX   Patent=US6071747;
RX   PubMed=9133667;
RX   PubMed=18283285;
RX   PubMed=22649407;
RX   PubMed=25925588;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-1531.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptome analysis by microarray.
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
CC   Cell type: Preadipocyte; CL=CL_0002334.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Children
CA   Transformed cell line
DT   Created: 26-09-16; Last updated: 29-06-23; Version: 10
//
RX   Patent=US6071747;
RA   Strosberg A.D., Zilberfarb V.;
RT   "Immortalized cell lines from human adipose tissue, process for
RT   preparing same and applications thereof.";
RL   Patent number US6071747, 06-Jun-2000.
//
RX   PubMed=9133667; DOI=10.1242/jcs.110.7.801;
RA   Zilberfarb V., Pietri-Rouxel F., Jockers R., Krief S., Delouis C.,
RA   Issad T., Strosberg A.D.;
RT   "Human immortalized brown adipocytes express functional
RT   beta3-adrenoceptor coupled to lipolysis.";
RL   J. Cell Sci. 110:801-807(1997).
//
RX   PubMed=18283285; DOI=10.1038/ijo.2008.10;
RA   van Beek E.A., Bakker A.H.F., Kruyt P.M., Vink C., Saris W.H.M.,
RA   Franssen-van Hal N.L.W., Keijer J.;
RT   "Comparative expression analysis of isolated human adipocytes and the
RT   human adipose cell lines LiSa-2 and PAZ6.";
RL   Int. J. Obes. 32:912-921(2008).
//
RX   PubMed=22649407; DOI=10.3389/fendo.2012.00013;
RA   Kazantzis M., Takahashi V., Hinkle J., Kota S., Zilberfarb V.,
RA   Issad T., Abdelkarim M., Chouchane L., Strosberg A.D.;
RT   "PAZ6 cells constitute a representative model for human brown
RT   pre-adipocytes.";
RL   Front. Endocrinol. 3:13.1-13.9(2012).
//
RX   PubMed=25925588; DOI=10.1186/s12967-015-0480-6;
RA   Guennoun A., Kazantzis M., Thomas R., Wabitsch M., Tews D.,
RA   Seetharama Sastry K., Abdelkarim M., Zilberfarb V., Strosberg A.D.,
RA   Chouchane L.;
RT   "Comprehensive molecular characterization of human adipocytes reveals
RT   a transient brown phenotype.";
RL   J. Transl. Med. 13:135.1-135.18(2015).
//