ID   XEMd-NH
AC   CVCL_GR64
SY   XEMd.NH
DR   Wikidata; Q54994670
RX   PubMed=1441600;
RX   PubMed=1793487;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=RGD; 2459; Cyp1a2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V38 ! V79NH
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 26-09-16; Last updated: 10-09-24; Version: 10
//
RX   PubMed=1441600; DOI=10.3109/00498259209051863;
RA   Doehmer J., Wolfel C., Dogra S., Doehmer C., Seidel A., Platt K.-L.,
RA   Oesch F., Glatt H.-R.;
RT   "Applications of stable V79-derived cell lines expressing rat
RT   cytochromes P4501A1, 1A2, and 2B1.";
RL   Xenobiotica 22:1093-1099(1992).
//
RX   PubMed=1793487; DOI=10.1002/mc.2940040613;
RA   Wolfel C., Platt K.-L., Dogra S., Glatt H.-R., Wachter F., Doehmer J.;
RT   "Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of
RT   17 beta-estradiol and 2-aminofluorene in V79 Chinese hamster cells.";
RL   Mol. Carcinog. 4:489-498(1991).
//