ID   XEM1
AC   CVCL_GR61
DR   Wikidata; Q54994667
RX   PubMed=1441600;
RX   PubMed=1692605;
RX   PubMed=8236270;
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=RGD; 2458; Cyp1a1.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
CC   Cell type: Fibroblast of lung; CL=CL_0002553.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4V36 ! V79MZ
SX   Male
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 26-09-16; Last updated: 10-09-24; Version: 10
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RX   PubMed=1441600; DOI=10.3109/00498259209051863;
RA   Doehmer J., Wolfel C., Dogra S., Doehmer C., Seidel A., Platt K.-L.,
RA   Oesch F., Glatt H.-R.;
RT   "Applications of stable V79-derived cell lines expressing rat
RT   cytochromes P4501A1, 1A2, and 2B1.";
RL   Xenobiotica 22:1093-1099(1992).
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RX   PubMed=1692605;
RA   Dogra S., Doehmer J., Glatt H.-R., Molders H., Siegert P., Friedberg T.,
RA   Seidel A., Oesch F.;
RT   "Stable expression of rat cytochrome P-450IA1 cDNA in V79 Chinese
RT   hamster cells and their use in mutagenicity testing.";
RL   Mol. Pharmacol. 37:608-613(1990).
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RX   PubMed=8236270; DOI=10.1016/0300-483x(93)90063-x;
RA   Doehmer J.;
RT   "V79 Chinese hamster cells genetically engineered for cytochrome P450
RT   and their use in mutagenicity and metabolism studies.";
RL   Toxicology 82:105-118(1993).
//