ID   EO771
AC   CVCL_GR23
SY   Eo771; E0771; EO 771
DR   ATCC; CRL-3461
DR   ChEMBL-Cells; CHEMBL4483168
DR   ChEMBL-Targets; CHEMBL4483234
DR   PubChem_Cell_line; CVCL_GR23
DR   Wikidata; Q54832331
RX   PubMed=16312045;
RX   PubMed=24391448;
RX   PubMed=32699527;
RX   PubMed=33026171;
WW   https://ch3biosystems.com/product/e0771/
CC   Characteristics: Belongs to the luminal subtype B; ERalpha-, ERbeta+, PR+ and ErbB2+ (PubMed=32699527).
CC   Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: C57BL/6.
ST   Source(s): Direct_author_submission
ST   Mouse STR 1-1: 17,18,19
ST   Mouse STR 1-2: 20,22
ST   Mouse STR 11-2: 15.3,16.3
ST   Mouse STR 12-1: 17,18
ST   Mouse STR 13-1: 17,18
ST   Mouse STR 15-3: 22.3,23.3
ST   Mouse STR 17-2: 15,16,17
ST   Mouse STR 18-3: 16,18
ST   Mouse STR 19-2: 13
ST   Mouse STR 2-1: 16,18
ST   Mouse STR 3-2: 14,15
ST   Mouse STR 4-2: 21.3,22.3,24.3
ST   Mouse STR 5-5: 17,21,22
ST   Mouse STR 6-4: 18,19,20,21
ST   Mouse STR 6-7: 15,16
ST   Mouse STR 7-1: 25.2,26,26.2
ST   Mouse STR 8-1: 16
ST   Mouse STR X-1: 27,29
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-09-24; Version: 11
//
RX   PubMed=16312045;
RA   Ewens A., Mihich E., Ehrke M.J.;
RT   "Distant metastasis from subcutaneously grown E0771 medullary breast
RT   adenocarcinoma.";
RL   Anticancer Res. 25:3905-3915(2005).
//
RX   PubMed=24391448; DOI=10.7150/ijbs.6309; PMCID=PMC3879588;
RA   Wang S.-H., Lu L., Fan Y.-Y., Wicha M.S., Cao Z.-Y., Chang A.E.,
RA   Xia J.-C., Baker J.R. Jr., Li Q.;
RT   "Characterization of a novel transgenic mouse tumor model for
RT   targeting HER2+ cancer stem cells.";
RL   Int. J. Biol. Sci. 10:25-32(2013).
//
RX   PubMed=32699527; DOI=10.1186/s12935-020-01418-1; PMCID=PMC7372867;
RA   Le Naour A., Koffi Y., Diab M., Le Guennec D., Rouge S., Aldekwer S.,
RA   Goncalves-Mendes N., Talvas J., Farges M.-C., Caldefie-Chezet F.,
RA   Vasson M.-P., Rossary A.;
RT   "EO771, the first luminal B mammary cancer cell line from C57BL/6
RT   mice.";
RL   Cancer Cell Int. 20:328.1-328.13(2020).
//
RX   PubMed=33026171; DOI=10.1002/cam4.3295; PMCID=PMC7643677;
RA   Le Naour A., Rossary A., Vasson M.-P.;
RT   "EO771, is it a well-characterized cell line for mouse mammary cancer
RT   model? Limit and uncertainty.";
RL   Cancer Med. 9:8074-8085(2020).
//