Cellosaurus cell line ASAN-PaCa (CVCL

Cellosaurus ASAN-PaCa (CVCL_GP71)

[Text version]

Cell line name

ASAN-PaCa

Synonyms

ASAN PaCa

Accession

CVCL_GP71

Resource Identification Initiative

To cite this cell line use: ASAN-PaCa (RRID:CVCL_GP71)

Comments

Problematic cell line: Contaminated. Shown to be a T3M-4 derivative (Direct_author_submission). Originally thought to originate from a 61 year old Caucasian female patient with a pancreatic intraductal papillary-mucinous carcinoma.
Population: Japanese.
Doubling time: 20 hours (PubMed=27518460).
Omics: Genomics; Whole exome sequencing.
Miscellaneous: STR profile and contamination by T3M-4 by personal communication of Giese, Nathalia A.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Heterozygous; Note=1 of 3 alleles (PubMed=27518460).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (PubMed=27518460).

Disease

Pancreatic ductal adenocarcinoma (NCIt: C9120)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_4056 (T3M-4)

Sex of cell

Male

Age at sampling

64Y

Category

Cancer cell line

STR profile

Source(s): Direct_author_submission

Markers:

Amelogenin	X
CSF1PO	10
D2S1338	17,25
D3S1358	14
D5S818	11
D7S820	11
D8S1179	16
D13S317	10,13
D16S539	11,12
D18S51	16
D19S433	14
D21S11	32.2,33.2
FGA	25,26
Penta D	10
Penta E	11,12
TH01	9.3
TPOX	11,12
vWA	18,19,21

Publications

PubMed=27518460; DOI=10.1097/MPA.0000000000000673
Heller A., Angelova A.L., Bauer S., Grekova S.P., Aprahamian M., Rommelaere J., Volkmar M., Janssen J.W.G., Bauer N., Herr I., Giese T., Gaida M.M., Bergmann F., Hackert T., Fritz S., Giese N.A.
Establishment and characterization of a novel cell line, ASAN-PaCa, derived from human adenocarcinoma arising in intraductal papillary mucinous neoplasm of the pancreas.
Pancreas 45:1452-1460(2016)

Cross-references

Cell line collections (Providers)

ABM; T8009 - Discontinued

Cell line databases/resources

cancercelllines; CVCL_GP71

Encyclopedic resources

Wikidata; Q54750668

Polymorphism and mutation databases

Cosmic; 2566118

Entry history

Entry creation

26-Sep-2016

Last entry update

10-Apr-2025

Version number