ID   KYSE-200
AC   CVCL_G698
SY   KYSE 200; KYSE200
DR   BioSample; SAMN03472503
DR   cancercelllines; CVCL_G698
DR   CGH-DB; 282-1
DR   CGH-DB; 9231-4
DR   Cosmic; 2650632
DR   Cosmic; 2698438
DR   IARC_TP53; 7682
DR   JCRB; JCRB1085
DR   JCRB; NIHS0364
DR   Wikidata; Q54900810
RX   PubMed=1728357;
RX   PubMed=7913084;
RX   PubMed=8575860;
RX   PubMed=11092977;
RX   PubMed=15172977;
RX   PubMed=16045545;
CC   Population: Japanese.
CC   Doubling time: 23.5 hours (PubMed=1728357).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg337Cys (c.1009C>T); ClinVar=VCV000142536; Zygosity=Unspecified (PubMed=8575860).
CC   Discontinued: JCRB; JCRB1085; probable.
CC   Discontinued: JCRB; NIHS0364; true.
CC   Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
ST   Source(s): JCRB=JCRB1085
ST   Amelogenin: X,Y
ST   CSF1PO: 10
ST   D13S317: 8
ST   D16S539: 9
ST   D5S818: 10,13
ST   D7S820: 9,11
ST   TH01: 9,10
ST   TPOX: 8
ST   vWA: 18,19
DI   NCIt; C4024; Esophageal squamous cell carcinoma
DI   ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   73Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 19-12-24; Version: 23
//
RX   PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C;
RA   Shimada Y., Imamura M., Wagata T., Yamaguchi N., Tobe T.;
RT   "Characterization of 21 newly established esophageal cancer cell
RT   lines.";
RL   Cancer 69:277-284(1992).
//
RX   PubMed=7913084; DOI=10.1002/ijc.2910580224;
RA   Kanda Y., Nishiyama Y., Shimada Y., Imamura M., Nomura H., Hiai H.,
RA   Fukumoto M.;
RT   "Analysis of gene amplification and overexpression in human
RT   esophageal-carcinoma cell lines.";
RL   Int. J. Cancer 58:291-297(1994).
//
RX   PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C;
RA   Tanaka H., Shibagaki I., Shimada Y., Wagata T., Imamura M.,
RA   Ishizaki K.;
RT   "Characterization of p53 gene mutations in esophageal squamous cell
RT   carcinoma cell lines: increased frequency and different spectrum of
RT   mutations from primary tumors.";
RL   Int. J. Cancer 65:372-376(1996).
//
RX   PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x; PMCID=PMC5926289;
RA   Pimkhaokham A., Shimada Y., Fukuda Y., Kurihara N., Imoto I.,
RA   Yang Z.-Q., Imamura M., Nakamura Y., Amagasa T., Inazawa J.;
RT   "Nonrandom chromosomal imbalances in esophageal squamous cell
RT   carcinoma cell lines: possible involvement of the ATF3 and CENPF genes
RT   in the 1q32 amplicon.";
RL   Jpn. J. Cancer Res. 91:1126-1133(2000).
//
RX   PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172;
RA   Sonoda I., Imoto I., Inoue J., Shibata T., Shimada Y., Chin K.,
RA   Imamura M., Amagasa T., Gray J.W., Hirohashi S., Inazawa J.;
RT   "Frequent silencing of low density lipoprotein receptor-related
RT   protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in
RT   esophageal squamous cell carcinoma.";
RL   Cancer Res. 64:3741-3747(2004).
//
RX   PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x; PMCID=PMC2517430;
RA   Ban S., Michikawa Y., Ishikawa K.-i., Sagara M., Watanabe K.,
RA   Shimada Y., Inazawa J., Imai T.;
RT   "Radiation sensitivities of 31 human oesophageal squamous cell
RT   carcinoma cell lines.";
RL   Int. J. Exp. Pathol. 86:231-240(2005).
//