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Cellosaurus YUDEDE (CVCL_G322)

[Text version]
Cell line name YUDEDE
Accession CVCL_G322
Resource Identification Initiative To cite this cell line use: YUDEDE (RRID:CVCL_G322)
Comments Part of: Yale University (YU) melanoma cell collection.
Omics: Deep exome analysis.
Derived from site: Metastatic; Pretibial, soft tissue; UBERON=UBERON_8480049+UBERON_0034929.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 83Y
Category Cancer cell line
Publications

PubMed=20149136; DOI=10.1111/j.1755-148X.2010.00685.x
Halaban R., Zhang W., Bacchiocchi A., Cheng E., Parisi F., Ariyan S., Krauthammer M., McCusker J.P., Kluger Y., Sznol M.
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells.
Pigment Cell Melanoma Res. 23:190-200(2010)

PubMed=22842228; DOI=10.1038/ng.2359
Krauthammer M., Kong Y., Ha B.H., Evans P., Bacchiocchi A., McCusker J.P., Cheng E., Davis M.J., Goh G., Choi M., Ariyan S., Narayan D., Dutton-Regester K., Capatana A., Holman E.C., Bosenberg M.W., Sznol M., Kluger H.M., Brash D.E., Stern D.F., Materin M.A., Lo R.S., Mane S., Ma S.-G., Kidd K.K., Hayward N.K., Lifton R.P., Schlessinger J., Boggon T.J., Halaban R.
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat. Genet. 44:1006-1014(2012)

PubMed=26214590; DOI=10.1038/ng.3361
Krauthammer M., Kong Y., Bacchiocchi A., Evans P., Pornputtapong N., Wu C., McCusker J.P., Ma S.-G., Cheng E., Straub R., Serin M., Bosenberg M.W., Ariyan S., Narayan D., Sznol M., Kluger H.M., Mane S., Schlessinger J., Lifton R.P., Halaban R.
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.
Nat. Genet. 47:996-1002(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_G322
Encyclopedic resources Wikidata; Q54995647
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number16