ID   SCCT3
AC   CVCL_G309
SY   SCC T3
DR   cancercelllines; CVCL_G309
DR   Cosmic; 1608870
DR   Wikidata; Q54952399
RX   PubMed=21602893;
RX   PubMed=22006338;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val216Met (c.646G>A); ClinVar=VCV000182965; Zygosity=Unspecified (PubMed=21602893).
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 11-02-13; Last updated: 19-12-24; Version: 12
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RX   PubMed=21602893; DOI=10.1038/onc.2011.180; PMCID=PMC3219832;
RA   Watt S.A., Pourreyron C., Purdie K.J., Hogan C., Killick-Cole C.L.,
RA   Foster N., Pratt N., Bourdon J.-C., Appleyard M.V.C.L., Murray K.,
RA   Thompson A.M., Mao X., Mein C.A., Bruckner-Tuderman L.K., Evans A.T.,
RA   McGrath J.A., Proby C.M., Foerster J., Leigh I.M., South A.P.;
RT   "Integrative mRNA profiling comparing cultured primary cells with
RT   clinical samples reveals PLK1 and C20orf20 as therapeutic targets in
RT   cutaneous squamous cell carcinoma.";
RL   Oncogene 30:4666-4677(2011).
//
RX   PubMed=22006338; DOI=10.1073/pnas.1114669108; PMCID=PMC3203814;
RA   Wang N.J., Sanborn Z., Arnett K.L., Bayston L.J., Liao W., Proby C.M.,
RA   Leigh I.M., Collisson E.A., Gordon P.B., Jakkula L.R., Pennypacker S.,
RA   Zou Y., Sharma M., North J.P., Vemula S.S., Mauro T.M., Neuhaus I.M.,
RA   LeBoit P.E., Hur J.S., Park K., Huh N., Kwok P.-Y., Arron S.T.,
RA   Massion P.P., Bale A.E., Haussler D., Cleaver J.E., Gray J.W.,
RA   Spellman P.T., South A.P., Aster J.C., Blacklow S.C., Cho R.J.;
RT   "Loss-of-function mutations in Notch receptors in cutaneous and lung
RT   squamous cell carcinoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:17761-17766(2011).
//