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Cellosaurus HepT1 (CVCL_G003)

[Text version]
Cell line name HepT1
Accession CVCL_G003
Resource Identification Initiative To cite this cell line use: HepT1 (RRID:CVCL_G003)
Comments Characteristics: Tumorigenic. Injection into nude mice gives rise to subcutaneous tumors (PubMed=8606490).
Doubling time: 1-2 days (PubMed=8606490).
Karyotypic information: Near tetraploid karyotype (PubMed=8606490).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 2Y10M
Category Cancer cell line
Publications

PubMed=8606490
Pietsch T., Fonatsch C., Albrecht S., Maschek H., Wolf H.K., von Schweinitz D.
Characterization of the continuous cell line HepT1 derived from a human hepatoblastoma.
Lab. Invest. 74:809-818(1996)

PubMed=10934159; DOI=10.1016/S0002-9440(10)64567-1; PMCID=PMC1850131
Weber R.G., Pietsch T., von Schweinitz D., Lichter P.
Characterization of genomic alterations in hepatoblastomas. A role for gains on chromosomes 8q and 20 as predictors of poor outcome.
Am. J. Pathol. 157:571-578(2000)

PubMed=12704668; DOI=10.1002/ijc.11082
Scheil S., Hagen S., Bruderlein S., Leuschner I., Behnisch W., Moller P.
Two novel in vitro human hepatoblastoma models, HepU1 and HepU2, are highly characteristic of fetal-embryonal differentiation in hepatoblastoma.
Int. J. Cancer 105:347-352(2003)

Cross-references
Encyclopedic resources Wikidata; Q54882877
Polymorphism and mutation databases Cosmic; 869287
Cosmic; 1237545
Entry history
Entry creation11-Feb-2013
Last entry update10-Apr-2025
Version number12