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Cellosaurus RAW-D (CVCL_F681)

[Text version]
Cell line name RAW-D
Synonyms RAW264 cell D; D clone; RAW264.7D; RAW264 cell Differentiation
Accession CVCL_F681
Resource Identification Initiative To cite this cell line use: RAW-D (RRID:CVCL_F681)
Comments Characteristics: Differentiates into osteoclast-like multinucleated cells at a very high rate even at low concentrations of RANKL (PubMed=14709158).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0493 (RAW 264.7)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=14709158; DOI=10.1677/joe.0.1800193
Watanabe T., Kukita T., Kukita A., Wada N., Toh K., Nagata K., Nomiyama H., Iijima T.
Direct stimulation of osteoclastogenesis by MIP-1alpha: evidence obtained from studies using RAW264 cell clone highly responsive to RANKL.
J. Endocrinol. 180:193-201(2004)

PubMed=15452179; DOI=10.1084/jem.20040518; PMCID=PMC2213286
Kukita T., Wada N., Kukita A., Kakimoto T., Sandra F., Toh K., Nagata K., Iijima T., Horiuchi M., Matsusaki H., Hieshima K., Yoshie O., Nomiyama H.
RANKL-induced DC-STAMP is essential for osteoclastogenesis.
J. Exp. Med. 200:941-946(2004)

PubMed=15812249; DOI=10.1089/jir.2005.25.227
Nomiyama H., Egami K., Wada N., Tou K., Horiuchi M., Matsusaki H., Miura R., Yoshie O., Kukita T.
Identification of genes differentially expressed in osteoclast-like cells.
J. Interferon Cytokine Res. 25:227-231(2005)

Cross-references
Encyclopedic resources Wikidata; Q54949256
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number11