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Cellosaurus XP2RO (CVCL_F496)

[Text version]
Cell line name XP2RO
Synonyms XP-2; Xeroderma Pigmentosum 2 ROtterdam; GM02415; GM-2415; GM 2415; GM2415; GM02415B; GM-1762; GM-708
Accession CVCL_F496
Resource Identification Initiative To cite this cell line use: XP2RO (RRID:CVCL_F496)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Xeroderma pigmentosum, complementation group E (NCIt: C114771)
Xeroderma pigmentosum (ORDO: Orphanet_910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_M225 (CW3-XPE)
Sex of cell Female
Age at sampling 34Y
Category Finite cell line
Publications

PubMed=4778857; DOI=10.1016/0027-5107(73)90062-6
Kleijer W.J., de Weerd-Kastelein E.A., Sluyter M.L., Keijzer W., de Wit J., Bootsma D.
UV-induced DNA repair synthesis in cells of patients with different forms of xeroderma pigmentosum and of heterozygotes.
Mutat. Res. 20:417-428(1973)

PubMed=4842087; DOI=10.1016/0027-5107(74)90013-x
de Weerd-Kastelein E.A., Keijzer W., Bootsma D.
A third complementation group in xeroderma pigmentosum.
Mutat. Res. 22:87-91(1974)

DOI=10.5962/bhl.title.4090
Coriell L.L., Greene A.E.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977)

PubMed=837385
Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A., de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P.
Repair of ultraviolet light damage in a variety of human fibroblast cell strains.
Cancer Res. 37:904-910(1977)

PubMed=273925; DOI=10.1073/pnas.75.4.1984; PMCID=PMC392467
Andrews A.D., Barrett S.F., Robbins J.H.
Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation.
Proc. Natl. Acad. Sci. U.S.A. 75:1984-1988(1978)

PubMed=3922833; DOI=10.20772/cancersci1985.76.3_162
Fujiwara Y., Satoh Y.
Assignment of two Japanese xeroderma pigmentosum patients to complementation group D and their characteristics.
Jpn. J. Cancer Res. 76:162-166(1985)

PubMed=4066782; DOI=10.1242/jcs.76.1.115
Johnson R.T., Squires S., Elliott G.C., Koch G.L.E., Rainbow A.J.
Xeroderma pigmentosum D-HeLa hybrids with low and high ultraviolet sensitivity associated with normal and diminished DNA repair ability, respectively.
J. Cell Sci. 76:115-133(1985)

PubMed=3010096; DOI=10.1016/0167-8817(86)90052-0
Barbis D.P., Schultz R.A., Friedberg E.C.
Isolation and partial characterization of virus-transformed cell lines representing the A, G and variant complementation groups of xeroderma pigmentosum.
Mutat. Res. 165:175-184(1986)

PubMed=3030788; DOI=10.1016/0014-4827(87)90214-X
Wood C.M., Timme T.L., Hurt M.M., Brinkley B.R., Ledbetter D.H., Moses R.E.
Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid.
Exp. Cell Res. 169:543-553(1987)

DOI=10.1007/978-1-4757-5016-4_9
Jaspers N.G.J., Roza L., Vermeulen W., Eker A.P.M., Taalman R.D.F.M., Hoeijmakers J.H.J., Bootsma D.
In vitro correction of cells from patients with mutagen hypersensitivity.
(In book chapter) DNA damage and repair; Castellani A. (eds.); pp.73-82; Springer; Boston; USA (1989)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=1376435; DOI=10.1016/0921-8777(92)90049-9
Keeney S.N., Wein H., Linn S.M.
Biochemical heterogeneity in xeroderma pigmentosum complementation group E.
Mutat. Res. 273:49-56(1992)

PubMed=8798680; DOI=10.1074/jbc.271.40.24317
Nichols A.F., Ong P., Linn S.M.
Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype.
J. Biol. Chem. 271:24317-24320(1996)

PubMed=8823375; DOI=10.1111/1523-1747.ep12584287
Moriwaki S.-i., Stefanini M., Lehmann A.R., Hoeijmakers J.H.J., Robbins J.H., Rapin I., Botta E., Tanganelli B., Vermeulen W., Broughton B.C., Kraemer K.H.
DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and Cockayne syndrome resemble xeroderma pigmentosum cells.
J. Invest. Dermatol. 107:647-653(1996)

PubMed=9584159; DOI=10.1128/mcb.18.6.3182; PMCID=PMC108900
Rapic-Otrin V., Kuraoka I., Nardo T., McLenigan M., Eker A.P.M., Stefanini M., Levine A.S., Wood R.D.
Relationship of the xeroderma pigmentosum group E DNA repair defect to the chromatin and DNA binding proteins UV-DDB and replication protein A.
Mol. Cell. Biol. 18:3182-3190(1998)

PubMed=10771487; DOI=10.1046/j.1523-1747.2000.00952.x
Itoh T., Linn S.M., Ono T., Yamaizumi M.
Reinvestigation of the classification of five cell strains of xeroderma pigmentosum group E with reclassification of three of them.
J. Invest. Dermatol. 114:1022-1029(2000)

PubMed=10777490; DOI=10.1074/jbc.M000960200
Nichols A.F., Itoh T., Graham J.A., Liu W., Yamaizumi M., Linn S.M.
Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.
J. Biol. Chem. 275:21422-21428(2000)

Cross-references
Cell line collections (Providers) ATCC; CRL-1259 - Discontinued
Coriell; GM00708 - Discontinued
Coriell; GM01762 - Discontinued
Coriell; GM02415
JCRB; KURB1079
JCRB; KURB1080
Cell line databases/resources CLO; CLO_0033096
Biological sample resources BioSample; SAMN00807747
Encyclopedic resources Wikidata; Q54837471
Entry history
Entry creation11-Feb-2013
Last entry update29-Jun-2023
Version number24