ID   XP25RO
AC   CVCL_F493
SY   XP-25; Xeroderma Pigmentosum 25 ROtterdam; GM00710; GM-710; GM0710; GM710; GM 0710A; GM710A; GM00710A
DR   CLO; CLO_0028892
DR   ATCC; CRL-1261
DR   Coriell; GM00710
DR   JCRB; KURB1039
DR   Wikidata; Q54836402
RX   CelloPub=CLPUB00447;
RX   DOI=10.5962/bhl.title.4090;
RX   PubMed=273925;
RX   PubMed=643622;
RX   PubMed=837385;
RX   PubMed=1034206;
RX   PubMed=1372102;
RX   PubMed=1702221;
RX   PubMed=4436596;
RX   PubMed=4778857;
RX   PubMed=4842087;
RX   PubMed=6096694;
RX   PubMed=6622549;
RX   PubMed=7161312;
RX   PubMed=8317483;
RX   PubMed=8643543;
RX   PubMed=9671271;
RX   PubMed=15450399;
RX   PubMed=22282976;
RX   PubMed=30165384;
CC   Population: Palestinian.
CC   Sequence variation: Mutation; HGNC; 12814; XPA; Simple; p.Arg207Ter (c.619C>T); ClinVar=VCV000000996; Zygosity=Homozygous (PubMed=1372102; PubMed=9671271; Coriell=GM00710).
CC   Discontinued: ATCC; CRL-1261; true.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3965; Xeroderma pigmentosum, complementation group A
DI   ORDO; Orphanet_910; Xeroderma pigmentosum
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y
CA   Finite cell line
DT   Created: 11-02-13; Last updated: 30-01-24; Version: 21
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992).
//
RX   DOI=10.5962/bhl.title.4090;
RA   Coriell L.L., Greene A.E.;
RT   "The human genetic mutant cell repository: list of genetic variants,
RT   chromosomal aberrations and normal cell cultures submitted to the
RT   repository. 4th edition. October 1977.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda; USA (1977).
//
RX   PubMed=273925; DOI=10.1073/pnas.75.4.1984; PMCID=PMC392467;
RA   Andrews A.D., Barrett S.F., Robbins J.H.;
RT   "Xeroderma pigmentosum neurological abnormalities correlate with
RT   colony-forming ability after ultraviolet radiation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 75:1984-1988(1978).
//
RX   PubMed=643622; DOI=10.1093/nar/5.3.951; PMCID=PMC342035;
RA   Kuhnlein U., Lee B., Penhoet E.E., Linn S.M.;
RT   "Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA
RT   endonuclease species with a low apparent Km.";
RL   Nucleic Acids Res. 5:951-960(1978).
//
RX   PubMed=837385;
RA   Lehmann A.R., Kirk-Bell S., Arlett C.F., Harcourt S.A.,
RA   de Weerd-Kastelein E.A., Keijzer W., Hall-Smith P.;
RT   "Repair of ultraviolet light damage in a variety of human fibroblast
RT   cell strains.";
RL   Cancer Res. 37:904-910(1977).
//
RX   PubMed=1034206; DOI=10.1016/0027-5107(76)90044-0;
RA   de Weerd-Kastelein E.A., Keijzer W., Sabour M., Parrington J.M.,
RA   Bootsma D.;
RT   "A xeroderma pigmentosum patient having a high residual activity of
RT   unscheduled DNA synthesis after UV is assigned to complementation
RT   group A.";
RL   Mutat. Res. 37:307-312(1976).
//
RX   PubMed=1372102; DOI=10.1016/0921-8777(92)90080-M;
RA   Satokata I., Tanaka K., Miura N., Narita M., Mimaki T., Satoh Y.,
RA   Kondo S., Okada Y.;
RT   "Three nonsense mutations responsible for group A xeroderma
RT   pigmentosum.";
RL   Mutat. Res. 273:193-202(1992).
//
RX   PubMed=1702221; DOI=10.1073/pnas.87.24.9908; PMCID=PMC55283;
RA   Satokata I., Tanaka K., Miura N., Miyamoto I., Satoh Y., Kondo S.,
RA   Okada Y.;
RT   "Characterization of a splicing mutation in group A xeroderma
RT   pigmentosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 87:9908-9912(1990).
//
RX   PubMed=4436596; DOI=10.1111/1523-1747.ep12676556;
RA   Der Kaloustian V.M., de Weerd-Kastelein E.A., Kleijer W.J., Keijzer W.,
RA   Bootsma D.;
RT   "The genetic defect in the de Sanctis-Cacchione syndrome.";
RL   J. Invest. Dermatol. 63:392-396(1974).
//
RX   PubMed=4778857; DOI=10.1016/0027-5107(73)90062-6;
RA   Kleijer W.J., de Weerd-Kastelein E.A., Sluyter M.L., Keijzer W.,
RA   de Wit J., Bootsma D.;
RT   "UV-induced DNA repair synthesis in cells of patients with different
RT   forms of xeroderma pigmentosum and of heterozygotes.";
RL   Mutat. Res. 20:417-428(1973).
//
RX   PubMed=4842087; DOI=10.1016/0027-5107(74)90013-x;
RA   de Weerd-Kastelein E.A., Keijzer W., Bootsma D.;
RT   "A third complementation group in xeroderma pigmentosum.";
RL   Mutat. Res. 22:87-91(1974).
//
RX   PubMed=6096694; DOI=10.1128/mcb.4.11.2341-2346.1984; PMCID=PMC369063;
RA   Abrahams P.J., Huitema B.A., van der Eb A.J.;
RT   "Enhanced reactivation and enhanced mutagenesis of herpes simplex
RT   virus in normal human and xeroderma pigmentosum cells.";
RL   Mol. Cell. Biol. 4:2341-2346(1984).
//
RX   PubMed=6622549; DOI=10.1111/j.1751-1097.1983.tb08373.x;
RA   Coohill T.P., Moore S.P., Grider R.A.;
RT   "Action spectra (254-302 nm) for four human photosensitive cell
RT   lines.";
RL   Photochem. Photobiol. 38:105-107(1983).
//
RX   PubMed=7161312; DOI=10.1007/BF00406246;
RA   Thielmann H.W., Popanda O., Edler L.;
RT   "XP patients from Germany: correlation of colony-forming ability,
RT   unscheduled DNA synthesis and single-strand breaks after UV damage in
RT   xeroderma pigmentosum fibroblasts.";
RL   J. Cancer Res. Clin. Oncol. 104:263-286(1982).
//
RX   PubMed=8317483; PMCID=PMC1682247;
RA   Vermeulen W., Jaeken J., Jaspers N.G.J., Bootsma D., Hoeijmakers J.H.J.;
RT   "Xeroderma pigmentosum complementation group G associated with
RT   Cockayne syndrome.";
RL   Am. J. Hum. Genet. 53:185-192(1993).
//
RX   PubMed=8643543; DOI=10.1073/pnas.93.10.5146; PMCID=PMC39422;
RA   Parshad R., Sanford K.K., Price F.M., Melnick L.K., Nee L.E.,
RA   Schapiro M.B., Tarone R.E., Robbins J.H.;
RT   "Fluorescent light-induced chromatid breaks distinguish Alzheimer
RT   disease cells from normal cells in tissue culture.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:5146-5150(1996).
//
RX   PubMed=9671271; DOI=10.1002/(SICI)1098-1004(1998)12:2<103::AID-HUMU5>3.0.CO;2-6;
RA   States J.C., McDuffie E.R., Myrand S.P., McDowell M.L., Cleaver J.E.;
RT   "Distribution of mutations in the human xeroderma pigmentosum group A
RT   gene and their relationships to the functional regions of the DNA
RT   damage recognition protein.";
RL   Hum. Mutat. 12:103-113(1998).
//
RX   PubMed=15450399; DOI=10.1016/j.mrfmmm.2004.02.013;
RA   Merkle T.J., O'Brien K., Brooks P.J., Tarone R.E., Robbins J.H.;
RT   "DNA repair in human fibroblasts, as reflected by host-cell
RT   reactivation of a transfected UV-irradiated luciferase gene, is not
RT   related to donor age.";
RL   Mutat. Res. 554:9-17(2004).
//
RX   PubMed=22282976; DOI=10.1093/carcin/1.1.21;
RA   Day R.S. 3rd, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A.,
RA   Mattern M.R.;
RT   "Human tumor cell strains defective in the repair of alkylation
RT   damage.";
RL   Carcinogenesis 1:21-32(1980).
//
RX   PubMed=30165384; DOI=10.1093/nar/gky774; PMCID=PMC6182131;
RA   Sabatella M., Theil A.F., Ribeiro-Silva C., Slyskova J., Thijssen K.,
RA   Voskamp C., Lans H., Vermeulen W.;
RT   "Repair protein persistence at DNA lesions characterizes XPF defect
RT   with Cockayne syndrome features.";
RL   Nucleic Acids Res. 46:9563-9577(2018).
//