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Cellosaurus INT-MEL-16/1 (CVCL_F250)

[Text version]
Cell line name INT-MEL-16/1
Synonyms Me9923/P; Me9923p; Me9923; Me 9923; 9923
Accession CVCL_F250
Resource Identification Initiative To cite this cell line use: INT-MEL-16/1 (RRID:CVCL_F250)
Sequence variations
  • Mutation; HGNC; HGNC:914; B2M; Simple; p.Asp79fs*6 (c.235_248del14); Zygosity=Homozygous (PubMed=9637706).
  • Mutation; HGNC; HGNC:914; B2M; Simple; p.Tyr86Ter (c.258C>G); Zygosity=Homozygous (PubMed=9637706).
HLA typing Source: PubMed=9637706
Class I
HLA-AA*02
HLA-BB*41,50
HLA-CC*w02,06
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_HE37 ! INT-MEL-16/2
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=9637706; DOI=10.1172/JCI498; PMCID=PMC508863
Hicklin D.J., Wang Z.-G., Arienti F., Rivoltini L., Parmiani G., Ferrone S.
Beta2-microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.
J. Clin. Invest. 101:2720-2729(1998)

DOI=10.1007/0-306-46872-7_16
Anichini A., Mortarini R., Vegetti C., Molla A., Borri A., Parmiani G.
Melanoma: the Milan melanoma cell lines.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.283-292; Kluwer Academic Publishers; New York; USA (1999)

DOI=10.13130/grazia-giulia_phd2016-02-18
Grazia G.
Co-targeting of oncogenic and death receptors pathways in human melanoma: pre-clinical rationale for a pro-apoptotic and anti-angiogenic strategy.
Thesis PhD (2015); Universita degli studi di Milano; Milano; Italy

Cross-references
Cell line databases/resources CLO; CLO_0001015
CLDB; cl141
Encyclopedic resources Wikidata; Q54897761
Polymorphism and mutation databases Cosmic; 720622
Cosmic; 2759875
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number13