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Cellosaurus HBEC3KTRL53 (CVCL_EQ79)

[Text version]
Cell line name HBEC3KTRL53
Accession CVCL_EQ79
Resource Identification Initiative To cite this cell line use: HBEC3KTRL53 (RRID:CVCL_EQ79)
Comments Knockout cell: Method=siRNA knockdown; HGNC; 11998; TP53.
Genetic integration: Method=Transduction; Gene=HGNC; 6407; KRAS (Note=With p.Gly12Val).
Genetic integration: Method=Transduction; Gene=HGNC; 11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_EQ78 (HBEC3KT53)
Sex of cell Female
Age at sampling 65Y
Category Telomerase immortalized cell line
Publications

PubMed=24240690; DOI=10.1038/onc.2013.486; PMCID=PMC4025984
Zaganjor E., Osborne J.K., Weil L.M., Diaz-Martinez L.A., Gonzales J.X., Singel S.M., Larsen J.E., Girard L., Minna J.D., Cobb M.H.
Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.
Oncogene 33:5457-5466(2014)

Cross-references
Encyclopedic resources Wikidata; Q54881416
Entry history
Entry creation26-Sep-2016
Last entry update10-Sep-2024
Version number15