Cellosaurus logo
expasy logo

Cellosaurus Hep-G2/PGC-1alpha wt (CVCL_EQ65)

[Text version]
Cell line name Hep-G2/PGC-1alpha wt
Accession CVCL_EQ65
Resource Identification Initiative To cite this cell line use: Hep-G2/PGC-1alpha wt (RRID:CVCL_EQ65)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 9237; PPARGC1A.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=17157261; DOI=10.1016/j.molcel.2006.10.012
Gaillard S., Grasfeder L.L., Haeffele C.L., Lobenhofer E.K., Chu T.-M., Wolfinger R., Kazmin D., Koves T.R., Muoio D.M., Chang C.-Y., McDonnell D.P.
Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.
Mol. Cell 24:797-803(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EQ65
Encyclopedic resources Wikidata; Q54882792
Gene expression databases GEO; GSM138631
GEO; GSM138632
GEO; GSM138633
Entry history
Entry creation26-Sep-2016
Last entry update10-Sep-2024
Version number14