Cellosaurus cell line iWS780-1.9 (CVCL

Cross-references
Cell line name	iWS780-1.9
Synonyms	WS iPSC from AG00780 (clone 1.9)
Accession	CVCL_EQ40
Resource Identification Initiative	To cite this cell line use: iWS780-1.9 (RRID:CVCL_EQ40)
Comments	Omics: Transcriptome analysis by microarray. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:12791; WRN; Simple; p.Arg369Ter (c.1105C>T) (c.1336C>T); ClinVar=VCV000005449; Zygosity=Homozygous (PubMed=24749076).
Disease	Werner syndrome (NCIt: C3447) Werner syndrome (ORDO: Orphanet_902)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_U282 (AG00780)
Sex of cell	Male
Age at sampling	60Y
Category	Induced pluripotent stem cell
Publications	PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587 Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C., Rennert O.M. Telomerase protects Werner syndrome lineage-specific stem cells from premature aging. Stem Cell Reports 2:534-546(2014)
Encyclopedic resources	Wikidata; Q54898390
Gene expression databases	GEO; GSM1184288 GEO; GSM1184289
Entry history
Entry creation	26-Sep-2016
Last entry update	19-Dec-2024
Version number	11