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Cellosaurus iWS229-p53i-2.1 (CVCL_EQ36)

[Text version]
Cell line name iWS229-p53i-2.1
Synonyms WS iPSC iWS229 p53i
Accession CVCL_EQ36
Resource Identification Initiative To cite this cell line use: iWS229-p53i-2.1 (RRID:CVCL_EQ36)
Comments Population: Japanese.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:11998; TP53.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_EQ35 (iWS229)
Sex of cell Male
Age at sampling 25Y
Category Induced pluripotent stem cell
Publications

PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587
Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C., Rennert O.M.
Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.
Stem Cell Reports 2:534-546(2014)

Cross-references
Encyclopedic resources Wikidata; Q54898386
Gene expression databases GEO; GSM1184294
GEO; GSM1184295
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number9