Cellosaurus cell line UCSD229i-SAD1-1 (CVCL

Cellosaurus UCSD229i-SAD1-1 (CVCL_EJ90)

Cross-references
Cell line name	UCSD229i-SAD1-1
Synonyms	sAD1.1; SAD1.1; UCSD-ADRC#8149-1
Accession	CVCL_EJ90
Resource Identification Initiative	To cite this cell line use: UCSD229i-SAD1-1 (RRID:CVCL_EJ90)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Disease	Alzheimer's disease (NCIt: C2866)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_EJ91 ! UCSD230i-SAD1-2 CVCL_EJ92 ! UCSD231i-SAD1-3
Sex of cell	Female
Age at sampling	83Y
Category	Induced pluripotent stem cell
Publications	PubMed=22278060; DOI=10.1038/nature10821; PMCID=PMC3338985 Israel M.A., Yuan S.H., Bardy C., Reyna S.M., Mu Y.-L., Herrera C.M., Hefferan M.P., Van Gorp S.F.J., Nazor K.L., Boscolo F.S., Carson C.T., Laurent L.C., Marsala M., Gage F.H., Remes A.M., Koo E.H., Goldstein L.S.B. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature 482:216-220(2012) PubMed=30686764; DOI=10.1016/j.stem.2018.12.013; PMCID=PMC6414424 van der Kant R., Langness V.F., Herrera C.M., Williams D.A., Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D., Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G., Goldstein L.S.B. Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons. Cell Stem Cell 24:363-375.e9(2019)
Cell line collections (Providers)	WiCell; ucsd229i-sad1-1
Cell line databases/resources	SKIP; SKIP005435
Encyclopedic resources	Wikidata; Q54990035
Entry history
Entry creation	26-Sep-2016
Last entry update	29-Jun-2023
Version number	12