ID   NDCS-1
AC   CVCL_EJ23
SY   NDCS1
DR   cancercelllines; CVCL_EJ23
DR   Cosmic; 1602482
DR   IARC_TP53; 25032
DR   Wikidata; Q54930340
RX   PubMed=17653762;
RX   PubMed=22057234;
CC   Population: Japanese.
CC   Doubling time: 30 hours (PubMed=17653762).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:5383; IDH2; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys242Ser (c.724T>A); ClinVar=VCV000376579; Zygosity=Unspecified (PubMed=17653762).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C6476; Dedifferentiated chondrosarcoma
DI   ORDO; Orphanet_55880; Chondrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 19-12-24; Version: 15
//
RX   PubMed=17653762; DOI=10.1007/s00428-007-0426-3;
RA   Kudo N., Ogose A., Hotta T., Kawashima H., Gu W.-G., Umezu H.,
RA   Toyama T., Endo N.;
RT   "Establishment of novel human dedifferentiated chondrosarcoma cell
RT   line with osteoblastic differentiation.";
RL   Virchows Arch. 451:691-699(2007).
//
RX   PubMed=22057234; DOI=10.1038/ng.1004; PMCID=PMC3427908;
RA   Marfatia T., van Eijk R., d'Adamo P., van Ruler M.A.J.H.,
RA   Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G.,
RA   Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L.,
RA   Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N.,
RA   Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M.,
RA   Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.;
RT   "Somatic mosaic IDH1 and IDH2 mutations are associated with
RT   enchondroma and spindle cell hemangioma in Ollier disease and Maffucci
RT   syndrome.";
RL   Nat. Genet. 43:1256-1261(2011).
//