ID   MIC
AC   CVCL_EI96
DR   cancercelllines; CVCL_EI96
DR   Cosmic; 2250464
DR   GEO; GSM5359676
DR   GEO; GSM5359677
DR   GEO; GSM5359678
DR   GEO; GSM5359679
DR   GEO; GSM5359680
DR   GEO; GSM5359681
DR   GEO; GSM5362930
DR   GEO; GSM5362931
DR   GEO; GSM5362932
DR   GEO; GSM5362933
DR   GEO; GSM5362934
DR   GEO; GSM5362935
DR   GEO; GSM5363981
DR   GEO; GSM5363982
DR   GEO; GSM5363983
DR   GEO; GSM5363984
DR   GEO; GSM5363985
DR   Wikidata; Q54905684
RX   DOI=10.5282/edoc.27750;
RX   PubMed=25223734;
RX   PubMed=36476851;
WW   Info; ESCLA; -; https://hgserver1.amc.nl/cgi-bin/r2/main.cgi?option=about_dscope
CC   Part of: Ewing Sarcoma Cell Line Atlas (ESCLA).
CC   From: Delattre, Olivier; Institut Curie; Paris; France.
CC   Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 1 fusion (Ex7/Ex6) (PubMed=36476851).
CC   Sequence variation: Mutation; HGNC; HGNC:11355; STAG2; Simple; p.Arg216Ter (c.646C>T); Zygosity=Unspecified (PubMed=25223734).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu285Lys (c.853G>A); ClinVar=VCV000420133; Zygosity=Unspecified (PubMed=25223734).
CC   Omics: Genomics; ChIP-seq; FLI1.
CC   Omics: Genomics; ChIP-seq; H3K27ac.
CC   Omics: Genomics; ChIP-seq; H3K27me3.
CC   Omics: Genomics; ChIP-seq; H3K4me3.
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Genomics; Whole genome sequencing.
CC   Omics: Proteomics.
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 26-09-16; Last updated: 10-04-25; Version: 11
//
RX   DOI=10.5282/edoc.27750;
RA   Orth, Martin Franz
RT   "Systematic multi-omics profiling of Ewing sarcoma cell lines.";
RL   Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany.
//
RX   PubMed=25223734; DOI=10.1158/2159-8290.CD-14-0622; PMCID=PMC4264969;
RA   Tirode, Franck
RA   Surdez, Didier
RA   Ma, Xiao-Tu
RA   Parker, Matthew
RA   Le Deley, Marie-Cecile
RA   Bahrami, Armita
RA   Zhang, Zhao-Jie
RA   Lapouble, Eve
RA   Grossetete-Lalami, Sandrine
RA   Rusch, Michael
RA   Reynaud, Stephanie
RA   Rio-Frio, Thomas
RA   Hedlund, Erin
RA   Wu, Gang
RA   Chen, Xiang
RA   Pierron, Gaelle
RA   Oberlin, Odile
RA   Zaidi, Sakina
RA   Lemmon, Gordon
RA   Gupta, Pankaj
RA   Vadodaria, Bhavin
RA   Easton, John
RA   Gut, Marta
RA   Ding, Li
RA   Mardis, Elaine R.
RA   Wilson, Richard K.
RA   Shurtleff, Sheila
RA   Laurence, Valerie
RA   Michon, Jean
RA   Marec-Berard, Perrine
RA   Gut, Ivo G.
RA   Downing, James R.
RA   Dyer, Michael Anthony
RA   Zhang, Jing-Hui
RA   Delattre, Olivier
RG   International Cancer Genome Consortium;
RG   St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project;
RT   "Genomic landscape of Ewing sarcoma defines an aggressive subtype with
RT   co-association of STAG2 and TP53 mutations.";
RL   Cancer Discov. 4:1342-1353(2014).
//
RX   PubMed=36476851; DOI=10.1016/j.celrep.2022.111761; PMCID=PMC10333306;
RA   Orth, Martin Franz
RA   Surdez, Didier
RA   Faehling, Tobias
RA   Ehlers, Anna C.
RA   Marchetto, Aruna
RA   Grossetete-Lalami, Sandrine
RA   Volckmann, Richard
RA   Zwijnenburg, Danny A.
RA   Gerke, Julia Sophie
RA   Zaidi, Sakina
RA   Alonso, Javier
RA   Sastre, Ana
RA   Baulande, Sylvain
RA   Sill, Martin
RA   Cidre-Aranaz, Florencia
RA   Ohmura, Shunya
RA   Kirchner, Thomas
RA   Hauck, Stefanie M.
RA   Reischl, Eva
RA   Gymrek, Melissa
RA   Pfister, Stefan Michael
RA   Strauch, Konstantin
RA   Koster, Jan
RA   Delattre, Olivier
RA   Grunewald, Thomas Georg Philipp
RT   "Systematic multi-omics cell line profiling uncovers principles of
RT   Ewing sarcoma fusion oncogene-mediated gene regulation.";
RL   Cell Rep. 41:111761.1-111761.28(2022).
//