Cellosaurus cell line C106 [Human melanoma] (CVCL

Cellosaurus C106 [Human melanoma] (CVCL_EI67)

Cross-references
Cell line name	C106 [Human melanoma]
Synonyms	C106M
Accession	CVCL_EI67
Resource Identification Initiative	To cite this cell line use: C106 [Human melanoma] (RRID:CVCL_EI67)
Comments	Characteristics: Early passage culture. Omics: SNP array analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Not specified.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (PubMed=22383533).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=22250051; DOI=10.1002/gcc.21932 Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S., O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K. Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene. Genes Chromosomes Cancer 51:452-461(2012) PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676 Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K. A high-throughput panel for identifying clinically relevant mutation profiles in melanoma. Mol. Cancer Ther. 11:888-897(2012)
Cell line databases/resources	cancercelllines; CVCL_EI67
Encyclopedic resources	Wikidata; Q54807829
Gene expression databases	GEO; GSM4178087
Entry history
Entry creation	26-Sep-2016
Last entry update	19-Dec-2024
Version number	7