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Cellosaurus C086 (CVCL_EI60)

[Text version]
Cell line name C086
Synonyms C086M
Accession CVCL_EI60
Resource Identification Initiative To cite this cell line use: C086 (RRID:CVCL_EI60)
Comments Characteristics: Early passage culture.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Not specified.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 27Y
Category Cancer cell line
Publications

PubMed=22250051; DOI=10.1002/gcc.21932
Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S., O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.
Genes Chromosomes Cancer 51:452-461(2012)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23890154; DOI=10.1111/pcmr.12153
Dutton-Regester K., Kakavand H., Aoude L.G., Stark M.S., Gartside M.G., Johansson P., O'Connor L., Lanagan C., Tembe V., Pupo G.M., Haydu L.E., Schmidt C.W., Mann G.J., Thompson J.F., Scolyer R.A., Hayward N.K.
Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma.
Pigment Cell Melanoma Res. 26:852-860(2013)

Cross-references
Encyclopedic resources Wikidata; Q54807645
Gene expression databases GEO; GSM4178080
Polymorphism and mutation databases Cosmic; 1665194
Cosmic; 2465276
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number7