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Cellosaurus C017 (CVCL_EI36)

[Text version]
Cell line name C017
Synonyms C017M
Accession CVCL_EI36
Resource Identification Initiative To cite this cell line use: C017 (RRID:CVCL_EI36)
Comments Characteristics: Early passage culture.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (PubMed=22383533).
  • Mutation; HGNC; HGNC:9612; PTK2B; Simple; p.Gly414Val (c.1241G>T); Zygosity=Heterozygous (PubMed=22383533).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=22250051; DOI=10.1002/gcc.21932
Dutton-Regester K., Aoude L.G., Nancarrow D.J., Stark M.S., O'Connor L., Lanagan C., Pupo G.M., Tembe V., Carter C.D., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
Identification of TFG (TRK-fused gene) as a putative metastatic melanoma tumor suppressor gene.
Genes Chromosomes Cancer 51:452-461(2012)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EI36
Encyclopedic resources Wikidata; Q54799990
Gene expression databases GEO; GSM4178060
Entry history
Entry creation26-Sep-2016
Last entry update19-Dec-2024
Version number7