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Cellosaurus A2780-DR (CVCL_EG64)

[Text version]
Cell line name A2780-DR
Accession CVCL_EG64
Resource Identification Initiative To cite this cell line use: A2780-DR (RRID:CVCL_EG64)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Omics: Proteome analysis.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25096996; DOI=10.1074/mcp.M113.033217; PMCID=PMC4223497
Jin L.-X., Huo Y., Zheng Z.-G., Jiang X.-Y., Deng H.-Y., Chen Y.-L., Lian Q.-Q., Ge R.-S., Deng H.-T.
Down-regulation of Ras-related protein Rab 5C-dependent endocytosis and glycolysis in cisplatin-resistant ovarian cancer cell lines.
Mol. Cell. Proteomics 13:3138-3151(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_EG64
Encyclopedic resources Wikidata; Q54606564
Proteomic databases PRIDE; PXD001176
PRIDE; PXD003252
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number11