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Cellosaurus JVE127 (CVCL_EG22)

[Text version]
Cell line name JVE127
Synonyms JVE-127
Accession CVCL_EG22
Resource Identification Initiative To cite this cell line use: JVE127 (RRID:CVCL_EG22)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~2-3 days (DSMZ=ACC-813).
Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.
Sequence variations
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (PubMed=26894854).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26894854).
Disease Colon mucinous adenocarcinoma (NCIt: C7966)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): DSMZ; PubMed=26894854

Markers:
AmelogeninX,Y
CSF1PO11
D2S133818,19
D3S135816,18
D5S81813
D7S8208,12
D8S117915
D13S3178,13
D16S53912,13
D18S5117
D19S43313,14
D21S1130
FGA24
Penta D10
Penta E4,16
TH017
TPOX11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391
Boot A., van Eendenburg J.D.H., Crobach S., Ruano D., Speetjens F., Calame J., Oosting J., Morreau H., van Wezel T.
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900
Boot A., Oosting J., van Eendenburg J.D.H., Kuppen P.J.K., Morreau H., van Wezel T.
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:E0184900-E0184900(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-813
Cell line databases/resources cancercelllines; CVCL_EG22
DepMap; ACH-002659
DSMZCellDive; ACC-813
Encyclopedic resources Wikidata; Q54899178
Gene expression databases GEO; GSM1655604
GEO; GSM1655627
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number15