ID   JVE015
AC   CVCL_EG16
SY   JVE-015
DR   cancercelllines; CVCL_EG16
DR   DepMap; ACH-002654
DR   DSMZ; ACC-786
DR   DSMZCellDive; ACC-786
DR   GEO; GSM1655597
DR   GEO; GSM1655623
DR   Wikidata; Q54899171
RX   PubMed=26894854;
RX   PubMed=28931069;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Doubling time: ~3-4 days (DSMZ=ACC-786).
CC   Microsatellite instability: Stable (MSS) (PubMed=26894854).
CC   Sequence variation: Mutation; HGNC; 583; APC; Simple; p.Arg1114Ter (c.3340C>T); ClinVar=VCV000236589; Zygosity=Heterozygous (PubMed=26894854; DepMap=ACH-002654).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=26894854; DepMap=ACH-002654).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Homozygous (DepMap=ACH-002654).
CC   Omics: DNA methylation analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
ST   Source(s): DSMZ=ACC-786; PubMed=26894854
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,12
ST   D16S539: 9
ST   D18S51: 15
ST   D19S433: 13,14
ST   D21S11: 30 (PubMed=26894854)
ST   D21S11: 30,32.2 (DSMZ=ACC-786)
ST   D2S1338: 18,19
ST   D3S1358: 16
ST   D5S818: 11,12
ST   D7S820: 9,11
ST   D8S1179: 13
ST   FGA: 23
ST   Penta D: 11
ST   Penta E: 11,12
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 02-05-24; Version: 14
//
RX   PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731;
RA   Boot A., van Eendenburg J.D.H., Crobach S., Ruano D., Speetjens F.,
RA   Calame J., Oosting J., Morreau H., van Wezel T.;
RT   "Characterization of novel low passage primary and metastatic
RT   colorectal cancer cell lines.";
RL   Oncotarget 7:14499-14509(2016).
//
RX   PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170;
RA   Boot A., Oosting J., van Eendenburg J.D.H., Kuppen P.J.K., Morreau H.,
RA   van Wezel T.;
RT   "Methylation associated transcriptional repression of ELOVL5 in novel
RT   colorectal cancer cell lines.";
RL   PLoS ONE 12:E0184900-E0184900(2017).
//