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Cellosaurus MB49luc (CVCL_E8D4)

[Text version]
Cell line name MB49luc
Synonyms MB49-luciferase; MB49 LucSH+
Accession CVCL_E8D4
Resource Identification Initiative To cite this cell line use: MB49luc (RRID:CVCL_E8D4)
Comments Characteristics: Transfected with a pSELECT-zeo-LucSh which contains a synthetic CpG-free firefly Luc-Zeocin fusion protein (PubMed=26921031).
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Mouse bladder transitional cell carcinoma (NCIt: C25823)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/ICRF-a(t).
Hierarchy Parent: CVCL_7076 (MB49)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages Provider; NCI TTC; TAB-4085/E-237-2018-0; https://techtransfer.cancer.gov/available-technologies?abstract=TAB-4085
Publications

PubMed=26921031; DOI=10.1158/2326-6066.CIR-15-0176; PMCID=PMC4881865
Vandeveer A.J., Fallon J.K., Tighe R.V., Sabzevari H., Schlom J., Greiner J.W.
Systemic immunotherapy of non-muscle invasive mouse bladder cancer with avelumab, an anti-PD-L1 immune checkpoint inhibitor.
Cancer Immunol. Res. 4:452-462(2016)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1