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Cellosaurus 2221 ERKOa (CVCL_E8CZ)

[Text version]
Cell line name 2221 ERKOa
Accession CVCL_E8CZ
Resource Identification Initiative To cite this cell line use: 2221 ERKOa (RRID:CVCL_E8CZ)
Comments Knockout cell: Method=KO mouse; MGI; MGI:1352467; Esr1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: B6.129-Esr1tm1Ksk (ERKO-alpha).
Category Transformed cell line
Publications

PubMed=19013153; DOI=10.1016/j.exer.2008.10.013; PMCID=PMC2637796
Catanuto P., Espinosa-Heidmann D.G., Pereira-Simon S., Sanchez P., Salas P.J., Hernandez E., Cousins S.W., Elliot S.J.
Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology.
Exp. Eye Res. 88:99-105(2009)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1