ID   SK-OV-3 SKN
AC   CVCL_E8BR
SY   SKN
RX   PubMed=8152906;
CC   Population: Caucasian.
CC   Characteristics: Control cell line for SK23a (Cellosaurus=CVCL_E8BP) and SK9 (Cellosaurus=CVCL_E8BQ) (PubMed=8152906).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C7978; Ovarian serous cystadenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0532 ! SK-OV-3
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
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RX   PubMed=8152906; DOI=10.1093/nar/22.6.1012; PMCID=PMC307923;
RA   Vikhanskaya F., Erba E., D'Incalci M., Broggini M.;
RT   "Introduction of wild-type p53 in a human ovarian cancer cell line not
RT   expressing endogenous p53.";
RL   Nucleic Acids Res. 22:1012-1017(1994).
//