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Cellosaurus HeLa-LTR-lacZ clone Z24 (CVCL_E8AP)

[Text version]
Cell line name HeLa-LTR-lacZ clone Z24
Synonyms HeLa LTR-lacZ clone Z24; Z24
Accession CVCL_E8AP
Resource Identification Initiative To cite this cell line use: HeLa-LTR-lacZ clone Z24 (RRID:CVCL_E8AP)
Comments Population: African American.
Characteristics: Transfected with a construct pMA175 containing the HIV-1 BRU LTR that allows expression of lacZ when Tat is present (PubMed=1560526).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_E8AQ (HeLa-H12)CVCL_E8AR (HeLa-P4)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=1560526; DOI=10.1128/JVI.66.5.2814-2820.1992; PMCID=PMC241038
Charneau P., Alizon M., Clavel F.
A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication.
J. Virol. 66:2814-2820(1992)

PubMed=7520946; DOI=10.1006/jmbi.1994.1542
Charneau P., Mirambeau G., Roux P., Paulous S., Buc H., Clavel F.
HIV-1 reverse transcription. A termination step at the center of the genome.
J. Mol. Biol. 241:651-662(1994)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1