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Cellosaurus WeWak1 (CVCL_E871)

[Text version]
Cell line name WeWak1
Synonyms Wewak1; WEWAK1; Wewak-1
Accession CVCL_E871
Resource Identification Initiative To cite this cell line use: WeWak1 (RRID:CVCL_E871)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Population: Papuan.
Virology: Contains a complete EBV genome (strain WeWak1) which has been sequenced (PubMed=25787276).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Caution: Could be identical to QIMR-WW1-LCL (Cellosaurus=CVCL_W930).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 7553; MYC; Simple; p.Pro72Thr (c.214C>A); Zygosity=Unspecified (PubMed=8108117).
HLA typing Source: IPD-IMGT/HLA=11558
Class I
HLA-AA*11:01,24:02
HLA-BB*27:04:01,15:06
HLA-CC*04:01,12:02
Class II
HLA-DPDPB1*01:01:01,03:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9583678; DOI=10.1038/sj.onc.1201704
Brimmell M., Mendiola R., Mangion J., Packham G.
BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability.
Oncogene 16:1803-1812(1998)

PubMed=25787276; DOI=10.1128/JVI.03614-14
Palser A.L., Grayson N.E., White R.E., Corton C., Correia S., Ba Abdullah M.M., Watson S.J., Cotten M., Arrand J.R., Murray P.G., Allday M.J., Rickinson A.B., Young L.S., Farrell P.J., Kellam P.
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.
J. Virol. 89:5222-5237(2015)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D.S., Willis A., Askar M., Fischer G.F., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan Otero M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) ECACC; 94022553
Cell line databases/resources dbMHC; 49061
IHW; IHW09219
IPD-IMGT/HLA; 11558
Encyclopedic resources Wikidata; Q54993790
Polymorphism and mutation databases Cosmic; 2804851
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number18