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Cellosaurus T5-1 (CVCL_E839)

[Text version]
Cell line name T5-1
Synonyms T5-1 (3.1.0); T51; T51 LCL; PGLC 33H(T5-1)
Accession CVCL_E839
Secondary accession CVCL_H270
Resource Identification Initiative To cite this cell line use: T5-1 (RRID:CVCL_E839)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=11419
Class I
HLA-AA*02:01:01:01
HLA-BB*08,27
Class II
HLA-DPDPA1*01:03:01
Disease Infectious mononucleosis (NCIt: C34726)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_JA31 (L33-6-1)
Children:
CVCL_B7M7 (6.1.6)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=4504337; DOI=10.1073/pnas.69.5.1244
Sato K., Slesinski R.S., Littlefield J.W.
Chemical mutagenesis at the phosphoribosyltransferase locus in cultured human lymphoblasts.
Proc. Natl. Acad. Sci. U.S.A. 69:1244-1248(1972)

PubMed=4599625; DOI=10.1073/pnas.70.8.2401
Orkin S.H., Buchanan P.D., Yount W.J., Reisner H., Littlefield J.W.
Lambda-chain production in human lymphoblast-mouse fibroblast hybrids.
Proc. Natl. Acad. Sci. U.S.A. 70:2401-2405(1973)

PubMed=62390; DOI=10.1111/j.1365-3083.1976.tb03029.x
Yount W.J., Utsinger P.D., Hutt L.M., Buchanan P.D., Korn J.H., Fuller C.R., Logue M., Pagano J.S.
Subpopulations of human lymphoblastoid cell lines. Correlation with the expression of surface receptors and content of Epstein-Barr virus genome.
Scand. J. Immunol. 5:795-810(1976)

PubMed=75508; DOI=10.1038/271459a0
Gladstone P., Pious D.A.
Stable variants affecting B cell alloantigens in human lymphoid cells.
Nature 271:459-461(1978)

Cross-references
Cell line collections (Providers) ECACC; 94071434
Cell line databases/resources dbMHC; 49031
IHW; IHW09284
IPD-IMGT/HLA; 11419
Encyclopedic resources Wikidata; Q54971583
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number14