| Comments |
Doubling time: ~30-40 hours (DSMZ=ACC-53); ~30 hours (CLS=300343). |
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| Sequence variations |
- Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln2459Ter (c.7375C>T); Zygosity=Heterozygous (PubMed=15472075).
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9585; PTCH1; Simple; p.Arg571Gln (c.1712G>A); ClinVar=VCV000819886; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly310Glu (c.929G>A); ClinVar=VCV000237678; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro153Alafs*28 (c.455dupC) (c.455_456insC) (p.P152fs) (c.459_460insC); ClinVar=VCV000182958; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1327 (KE-37) |
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| Sex of cell |
Male |
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| Age at sampling |
27Y |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): CLS=300343; DSMZ=ACC-53; RCB=RCB1168; TKG=TKG 0247
Markers:| Amelogenin | X,Y |
| CSF1PO | 10,12 |
| D1S1656 | 15.3,16 |
| D2S1338 | 19,25 |
| D3S1358 | 15,18 |
| D5S818 | 12,13 |
| D6S1043 | 18,21 |
| D7S820 | 8,12 |
| D8S1179 | 11,14 |
| D12S391 | 19,22 |
| D13S317 | 8,12 |
| D16S539 | 11,12 |
| D18S51 | 13,18 |
| D19S433 | 13,15 |
| D21S11 | 28,29,30 (CLS=300343)
28,30 (DSMZ=ACC-53) |
| FGA | 24,25 |
| Penta D | 11,15 |
| Penta E | 5,14 |
| TH01 | 6,9.3 |
| TPOX | 8 |
| vWA | 17,18 |
Run an STR similarity search on this cell line |
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 33 |
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