ID   BOWES pCMV6 clone #1
AC   CVCL_E7UN
SY   BOWES PCMV6
RX   PubMed=25798946;
CC   Population: Caucasian.
CC   Characteristics: Control cell line for the BOWES CXCR3 cell lines (PubMed=25798946).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Trp110Ter (c.330G>A) (p.Gly125Arg, c.373G>A); ClinVar=VCV000376303; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3317 ! HMCB
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 14-08-25; Version: 2
//
RX   PubMed=25798946; DOI=10.1371/journal.pone.0121140; PMCID=PMC4370421;
RA   Jenkins, Molly Harris
RA   Brinckerhoff, Constance Elizabeth
RA   Mullins, David Warren
RT   "CXCR3 signaling in BRAFWT melanoma increases IL-8 expression and
RT   tumorigenicity.";
RL   PLoS ONE 10:e0121140.1-e0121140.17(2015).
//