Cellosaurus cell line MCF7(Cas9) (CVCL

Entry history
Cell line name	MCF7(Cas9)
Accession	CVCL_E7J9
Resource Identification Initiative	To cite this cell line use: MCF7(Cas9) (RRID:CVCL_E7J9)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0031 (MCF-7)
Sex of cell	Female
Age at sampling	69Y
Category	Cancer cell line
Web pages	Provider; BRICS; ECC3035; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3969
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1