ID   SKOV3.A2.1E4
AC   CVCL_E7IY
SY   SKOV3.A2
RX   PubMed=7539040;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4931; HLA-A (Note=Allele A*02.01).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C7978; Ovarian serous cystadenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0532 ! SK-OV-3
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=7539040; DOI=10.1084/jem.181.6.2109; PMCID=PMC2192068;
RA   Fisk B., Blevins T.L., Wharton J.T., Ioannides C.G.;
RT   "Identification of an immunodominant peptide of HER-2/neu
RT   protooncogene recognized by ovarian tumor-specific cytotoxic T
RT   lymphocyte lines.";
RL   J. Exp. Med. 181:2109-2117(1995).
//