Cellosaurus hURO18H7 IQAD biosensor (CVCL_E7CP)
| Cell line name | hURO18H7 IQAD biosensor |
|---|---|
| Synonyms | hURO18H7 caspase-1 biosensor |
| Accession | CVCL_E7CP |
| Resource Identification Initiative | To cite this cell line use: hURO18H7 IQAD biosensor (RRID:CVCL_E7CP) |
| Comments | Characteristics: Can be used as a biosensor to measure caspase-1 induced cellular inflammatory responses to when infected bacterial urinary pathogens (CelloPub=CLPUB007899). Characteristics: Transduced with a firefly luciferase reporter circularly permuted in which the N- and C-terminal domains are physically separated by a flexible hinge region containing a caspase-1 cleaving site (IQADSGPIG) (CelloPub=CLPUB00789). Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=Circ. permuted with an IQAD caspase-1 site). Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Donor information: Established from a perimenopausal female patient undergoing urogynecological surgery for stress urinary incontinence (from parent cell line). Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. Cell type: Urothelial cell; CL=CL_0000731. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_E7CN (hURO18H7) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Transformed cell line |
| Publications | CLPUB00789 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |