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Cellosaurus MOU (CVCL_E782)

[Text version]
Cell line name MOU
Synonyms MANN; Mann; MANN2; GM08605
Accession CVCL_E782
Resource Identification Initiative To cite this cell line use: MOU (RRID:CVCL_E782)
Comments Part of: 10th International Histocompatibility Workshop (10IHW) cell line panel.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: HLA class II peptidome analysis by proteomics.
Omics: MHC region genome.
Derived from sampling site: Peripheral blood.
HLA typing Source: IPD-IMGT/HLA=11096
Class I
Class II
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line

PubMed=6200433; DOI=10.1007/BF00364762
Brodsky F.M.
A matrix approach to human class II histocompatibility antigens: reactions of four monoclonal antibodies with the products of nine haplotypes.
Immunogenetics 19:179-194(1984)

Yang S.Y., Milford E., Hammerling U., Dupont B.
Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B-cell line panel designed for the Tenth International Histocompatibility Workshop.
(In) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.11-19; Springer; New York (1989)

Mickelson E., Reinsmoen N., Robbins F.-M., Hartzman R.J., Odum N., Svejgaard A., Farrell C., Honeyman M., Flomenberg N., Sell T., Eckels D.
HLA-Dw and HLA-DP typing of the reference panel of B-lymphoblastoid cell lines.
(In) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.38-42; Springer; New York (1989)

Yang S.Y.
Assignment of HLA-A and HLA-B antigens for the reference panel of B-lymphoblastoid cell lines determined by one-dimensional isoelectric focusing (lD-IEF) gel electrophoresis.
(In) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.43-44; Springer; New York (1989)

Knowles R.W.
Assignment of HLA-class II alpha and beta chain 2-D gel patterns for the workshop reference panel of B-lymphoblastoid cell lines.
(In) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.44-46; Springer; New York (1989)

Flomenberg N.
Assignment of T-cell-defined (TCD) HLA class II specificities for the reference panel of B-lymphoblastoid cell lines.
(In) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.46-48; Springer; New York (1989)

Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=8307784; DOI=10.1016/0198-8859(93)90514-2
Degli-Esposti M.A., Griffiths M.S.J., Daly L.N., Witt C.S., Simons M., Carcassi C., Albert E.D., Giphart M.J., Dawkins R.L.
Characterization of 4AOHW cell line panel including new data for the 10IHW panel.
Hum. Immunol. 38:3-16(1993)

PubMed=8813743; DOI=10.1111/j.1399-0039.1996.tb02596.x
Prasad V.K., Yang S.Y.
Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines.
Tissue Antigens 47:538-546(1996)

PubMed=18193213; DOI=10.1007/s00251-007-0262-2
Horton R., Gibson R., Coggill P., Miretti M.M., Allcock R.J.N., Almeida-King J., Forbes S., Gilbert J.G.R., Halls K., Harrow J.L., Hart E., Howe K.L., Jackson D.K., Palmer S., Roberts A.N., Sims S., Stewart C.A., Traherne J.A., Trevanion S., Wilming L.G., Rogers J., de Jong P.J., Elliott J.F., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics 60:1-18(2008)

PubMed=25502872; DOI=10.1007/s00251-014-0819-9
Bergseng E., Dorum S., Arntzen M.O., Nielsen M., Nygard S., Buus S., de Souza G.A., Sollid L.M.
Different binding motifs of the celiac disease-associated HLA molecules DQ2.5, DQ2.2, and DQ7.5 revealed by relative quantitative proteomics of endogenous peptide repertoires.
Immunogenetics 67:73-84(2015)

PubMed=28360230; DOI=10.1101/gr.213538.116
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W.-H., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

PubMed=29171935; DOI=10.1111/tan.13184
Turner T.R., Hayhurst J.D., Hayward D.R., Bultitude W.P., Barker D.J., Robinson J., Madrigal J.A., Mayor N.P., Marsh S.G.E.
Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 international HLA and immunogenetics workshop cell lines.
HLA 91:88-101(2018)

Cell line collections Coriell; GM08605
ECACC; 88052050
Cell line databases/resources CLO; CLO_0010607
dbMHC; 48977
IHW; IHW09050
Encyclopedic resources Wikidata; Q54906413
Proteomic databases PRIDE; PXD001205
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number22